This How-to-Paper outlines strategies for promoting business models that support rural youth employment in the agri-food sector in Sub-Saharan Africa. It emphasizes the need for viable models specifically tailored to youth and women in the context of rural areas, considering factors like market potential, employment creation, and financial as well as geographical accessibility. The paper discusses the process of prioritizing agricultural value chains, analysing youth-friendly business opportunities, and identifying the necessary technical and entrepreneurial skills set for successful promotion through local partnerships. Finally, it explores case studies highlighting experiences, key details, and lessons learned from various business models in production, processing, and service provision in four countries.